Bronchiolitis

Program Currently On Hold Due to COVID-19 Pandemic

Clinical Program

Program Currently On Hold Due to COVID-19 Pandemic

We have completed two double-blind, randomized, single-center, 2-arm studies. The primary objectives were to study the safety and tolerability of 160 ppm nitric oxide intermittent inhalation treatment in 2- to 12-month old subjects admitted to hospital and diagnosed with acute bronchiolitis. The planned secondary objectives were to assess the efficacy of NO intermittent inhalation treatment (in addition to standard O2 treatment) compared to standard O2 treatment alone, assessed as the LOS, clinical score improvement, and length of standard O2 treatment.

A Leading Cause of Global Child Mortality

Bronchiolitis

A Leading Cause of Global Child Mortality

Bronchiolitis is an infection of the small airways. It is also the most common manifestation of acute lower respiratory infection (ALRI) in early infancy, and is the leading cause of global child mortality. Viral bronchiolitis is currently the most common reason for pediatric hospital admission in the US, accounting for almost 20% of all-cause infant hospitalizations. Viral etiology is the main cause, and among the respiratory viruses, respiratory syncytial virus (RSV) is believed to be the most important viral pathogen causing ALRI in young children.

Worldwide, it is estimated that 60,000 to 199,000 children younger than 5 years die yearly from RSV-associated ALRI, with 99% of these deaths occurring in developing countries. The disease is common mainly in the first year of life. The clinical signs and symptoms are consistent with hypoxia, difficulty breathing, coryza, poor feeding, cough, wheeze and crepitations on auscultation, and in some cases respiratory failure.

LungFit for Bronchiolitis

LungFit for Bronchiolitis

Learn More about LungFit PRO

Our Technology

Simple, safe and convenient

Easy to Use

Portable

One system can treat multiple patients

One Respiratory Therapist (RT) can operate multiple systems

Demonstrated Safety Record

Safely delivering high concentration nitric oxide for lung infections

The Beyond Air Nitric Oxide Delivery System has a demonstrated safety record at concentrations of 150-250 ppm.

2,500+

treatments administered

140+

patients

9

different clinical settings

0

serious adverse events (SAEs) related to NO.

Source

Several animal toxicity studies have been completed showing no differences from control up to 400 ppm.

Important Safety Information

Caution - LungFit is an Investigational Device, Limited by Federal (or United States) Law to Investigational Use.